k current — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8581	Flecainide hydrochloride		Others
	Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.		Others
T6541	Ibutilide Fumarate	Corvert Fumarate,U70226E	Calcium Channel , Sodium Channel
	Ibutilide Fumarate (U70226E) is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium current rather than by blocking outwar...		Calcium Channel , Sodium Channel
T3574	Sematilide hydrochloride	CK-1752A,CK-1752,Sematilide HCl	Potassium Channel
	Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the ...		Potassium Channel
TP1858L	Phe-Met-Arg-Phe, amide acetate	Phe-Met-Arg-Phe, amide acetate（64190-70-1 freebase)	Potassium Channel
	Phe-Met-Arg-Phe, amide acetate dose dependently (ED50=23 nM) activates a K+ current in the peptidergic caudodorsal neurons. This peptide appears to localize with neuropeptide Y in some regions of the brain.		Potassium Channel
T15758	Linopirdine	DuP 996	Potassium Channel , TRP/TRPV Channel
	Linopirdine (DuP 996) is a TRPV1 agonist. Linopirdine is an orally active and selective M-type K+ current (IM; Kv7; KCNQ Channels) inhibitor (IC50: 2.4 μM). Linopirdine is a cognitive enhancer. It acts by stimulating rel...		Potassium Channel , TRP/TRPV Channel
T31488	Dimethindene	Dimetindeno,Z 2001,Dimetindene,Z-2001,Z2001	Potassium Channel , Endogenous Metabolite , AChR , Histamine Receptor
	Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects.
T4A2458	Resibufogenin	Bufogenin,Recibufogenin	Others
	1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological eff...		Others
T0723	Cloperastine hydrochloride	HT-11 hydrochloride	Potassium Channel , 5-HT Receptor
	Cloperastine hydrochloride (HT-11 hydrochloride) is a type of flavonoid.		Potassium Channel , 5-HT Receptor
T13619	Cloperastine fendizoate	Hustazol	EGFR
	Cloperastine fendizoate (Hustazol) inhibits the hERG K+ currents in a concentration-dependent manner (IC50: 27 nM).		EGFR
T0866	Propafenone	Rythmol,Propafenonum	Potassium Channel , MRP , Sodium Channel
	Propafenone (Propafenonum) is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity....		Potassium Channel , MRP , Sodium Channel
T22662	Chromanol 293B		Others
	slow delayed rectifier K+ current (IKs) blocker		Others
T14189	Almokalant	H 234/09	Potassium Channel
	Almokalant is a class III antiarrhythmic drug, acts as a potassium channel blocker. And it inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current.		Potassium Channel
TP1440	Phe-Met-Arg-Phe amide trifluoroacetate
	Phe-met-arg-phe amide trifluoroacetate is an activator of K+ current with an ED50 of 23nm on the fundus nerve.
TN3636	Chlorahololide C		Potassium Channel
	Chlorahololide C is a potent and selective potassium channel blocker, it exerts potent and selective inhibition on the delayed rectifier (I(K)) K(+) current with the IC(50) value of 3.6 +/- 10.1 mu M.		Potassium Channel
TP2090	AmmTX3
	KV4 channel blocker. Blocks A-type K+ current (ISA) in mouse cerebellar granule neurons. The accessory dipeptidyl peptidase-like proteins (DPP) 6 and 10 are required for blockade.
TP1858	Phe-Met-Arg-Phe, amide
	Phe-Met-Arg-Phe, amide dose dependently (ED50=23 nM) activates a K+ current in the peptidergic caudodorsal neurons. This peptide appears to localize with neuropeptide Y in some regions of the brain.
T80036	AmmTX3 TFA		Potassium Channel
	AmmTX3 TFA, a peptide toxin derived from Androctonus mauretanicus scorpion venom, functions as a selective blocker of the K_v4 channel. It inhibits the A-type K^+ current with an inhibition constant (K_i) of 131 nM [1] [...		Potassium Channel
T68499	F15845 HBr
	F 15845 is a blocker of the persistent sodium current prevents consequences of hypoxia in rat femoral artery. F15845 has been shown to selectively inhibit the persistent sodium current of Nav1.5[1] exerting cardioprotect...
T12879	Sematilide	CK-1752	Others
	Sematilide is a blocker of selective IKr channel.		Others
T61197	Irdabisant hydrochloride
	Irdabisant hydrochloride (CEP-26401) is a selective, orally active, and blood-brain barrier (BBB) penetrant histamine H3 receptor (H3R) inverse agonist/inverse agonist, demonstrating high affinity with K*i values of 7.2 ...